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About

Parkinson's disease, often referred to as PD, is a complex and progressive neurological disorder that significantly affects a person's ability to control movement and, in some cases, their cognitive and emotional well-being.The primary cause of Parkinson's disease is thought to be the slow deterioration of particular neurons, which is thought to be the outcome of a complicated interaction between environmental and genetic factors. IndiGenesPD provides information related to genes,mutation and drugs of PD in Indian population.

Genes

Serial No
Gene ID
Gene Name
Protein ID
1
348
APOE
P02649
2
23400
ATP13A2
Q9NQ11
3
627
BDNF
P23560
4
729230
CCR2
P41597
5
1234
CCR5
P51681
6
51142
CHCHD2
Q9Y6H1
7
1621
DBH
P09172
8
1813
DRD2
P14416
9
1814
DRD3
P35462
10
1815
DRD4
P21917
11
1981
EIF4G1
Q04637
12
26281
FGF20
Q9NP95
13
2629
GBA
P04062
14
2643
GCH1
P30793
15
9446
GSTO1
P78417
16
120892
LRRK2
Q5S007
17
4137
MAPT
P10636
18
6347
MCP1
Q8NEM0
19
10
NAT2
P11345
20
4842
NOS1
P29475
21
1728
NQO1
P15559
22
5071
PARK2
O60260
23
11315
PARK7
Q99497
24
65018
PINK1
Q9BXM7
25
8398
PLA2G6
O60733
26
5420
PODXL
Q15165
27
5445
PON2
Q15165
28
6352
RANTES
P13501
29
79608
RIC3
Q7Z5B4
30
6622
SNCA
P37840
31
8867
SYNJ1
O43426
32
55737
VPS35
Q96QK1

Mutation

Serial No
Gene Name
SNP ID
1
APOE

rs449647

rs405509

rs429358

rs7412

2
BDNF

rs56164415

rs6265

3
DBH

rs129882

4
DRD2

rs1800498

rs17294542

5
DRD3

rs905568

6
FGF20

rs1721100

rs2720208

7
GBA

rs2075569

rs114099990

rs28373017

8
GSTO1

rs4925

9
LRRK2

rs2421947

10
MAPT

rs1467967 , rs242557

rs3785883 , rs2471738


11
NQO1

rs1800566

12
PARK2

rs1801474

rs1801582

13
PARK7

rs56327722

rs2641116

14
PINK1

rs3738133 , rs7550319

rs3131713 , rs3738136


15
PLA2G6

rs121908686

16
PON2

rs7493

17
RIC3

rs778138358

rs777471396

Drugs

Ashwagandha

Levodopa

Read More >

Dopamine Agonist

Monoamine Oxidase B inhibitor

​Tabebuia impetiginosa bark extracts

Mucuna pruriens  seeds aqueous extracts

Bicyclogermacrene

Trihexyphenidyl

​Catechol-O-Methyl Transferase inhibitor

​Withania somnifera root extract

Levodopa Carbidopa therapy

​Curcumin

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